Sliding Microtomes

A sliding microtome is a laboratory instrument used to cut thin slices (typically less than 20 micrometers thick) of biological tissue samples. It is called a “sliding microtome” because it uses a sliding motion to make the cuts.

Sliding microtomes work by holding the tissue sample in place with a clamp or other mechanism and then using a sharp blade to slice the tissue into thin sections. The tissue sample is placed on a platform and moved through the blade in a sliding motion, with the blade making a series of closely spaced cuts as it moves. The thickness of the slices can be adjusted by changing the distance between the blade and the platform or by using blades with different thicknesses.

Sliding microtomes are commonly used in histology, which is the study of tissues at the microscopic level. They are an essential tool for preparing tissue samples for examination under a microscope and are used in a wide range of applications, including diagnosing diseases, studying the effects of drugs on tissues, and researching the structure and function of tissues.

Sliding microtomes are also used in a variety of other applications, including the production of very thin slices of materials such as metals and ceramics for use in electron microscopy and other types of materials analysis.

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